Clinical and Applied Thrombosis/Hemostasis

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
1076029607304096v1
14/1/112    most recent
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gumus, I. I.
Right arrow Articles by Turhan, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gumus, I. I.
Right arrow Articles by Turhan, N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
This version was published on January 1, 2008
Clinical and Applied Thrombosis/Hemostasis, Vol. 14, No. 1, 112-115 (2008)
DOI: 10.1177/1076029607304096

Multifactorial Thrombophilia in a Pregnancy: A Case Report

Ilknur Inegol Gumus, MD

Department of Obstetrics and Gynecology Fatih University Faculty of Medicine, Ankara, Turkey, ilknurinegol{at}yahoo.com

Hilal Uslu, MD

Department of Obstetrics and Gynecology Fatih University Faculty of Medicine, Ankara, Turkey

Nuket Bavbek, MD

Department of Internal Medicine Fatih University Faculty of Medicine, Ankara, Turkey

Nilgun Turhan, MD

Department of Internal Medicine Fatih University Faculty of Medicine, Ankara, Turkey

Thrombophilias are inherited or acquired conditions that predispose individuals to thromboembolism. Thrombophilic disorders increase obstetric complications, such as early pregnancy loss, fetal growth retardation, placental abruption, and preeclampsia. Recurrent pregnancy loss affects 1% to 3% of women of reproductive age, and a large proportion of these losses remain unexplained. Thrombophilic defects were found in 49% to 65% of women with pregnancy complications compared with 18% to 22% of women with normal pregnancies, suggesting a 3- to 8-fold increase in risk. We report a case of a pregnant woman who had a history of recurrent pregnancy losses that was complicated with protein S deficiency, factor V Leiden mutation, methylene tetrahydrofolate reductase mutation, and antiphospholipid syndrome in her pregnancy.

Key Words: factor V Leiden mutation • methylene tetrahydrofolate reductase mutation • protein S deficiency • pregnancy


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?